How You Help Change the Story

Just like Lou Gehrig, Melissa Pezzolesi heard the same life-changing words: “You have ALS.”

But because of Lou’s legacy and supporters like you, her story didn’t end at the diagnosis. Through Live Like Lou’s Connect & Serve program, Melissa’s family received the support they needed when daily tasks became overwhelming.

“They arrived bright and early this morning and took on several projects, accomplishing what would have taken us several weeks or months in just a few hours… They truly cared.”

Melissa Pezzolesi, diagnosed with ALS in 2025

Help Us Serve More ALS Families in 2026 and Beyond.
Turn compassion into action. Make your year-end gift today.

"today i consider myself the luckiest man on the face of the earth."

Lou said those words surrounded by love and unwavering support.

If he could see the fight against ALS today, he’d see your generosity strengthening the legacy he created.

He might remind us:

→ALS is still relentless, but so is generosity.
→Families still face unimaginable challenges, but they don’t face them alone.
→Every gift moves us closer to better care, stronger support, and the research breakthroughs we urgently need.

GIVE TODAY

donate today

Your gift of any amount will help Live Like Lou achieve its vision to leave ALS better than we found it.

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Live Like Lou Foundation

2 S. Campus Avenue

Oxford, OH 45056

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